Pharmaceutical giants to join US initiative for rheumatoid arthritis

Posted by Jimbo | Posted in | Posted on 6:50 PM

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New York - Government researchers will collaborate with 10 large pharmaceutical companies on a $230-million initiative to speed development of new medications for major diseases, the US National Institutes of Health announced on Tuesday. 

 
The five-year initiative targets Alzheimer's Disease, type 2 diabetes, rheumatoid arthritis and lupus, and may be expanded to other ailments, the NIH said. 

The goal is to pool resources among NIH and the companies, normally vigorous competitors, to enable analysis of large data sets to track disease progression and the effect of therapies.
Data and early-stage research will be shared and made publicly available, and companies are expected to compete on developing commercial drugs once research passes the preliminary phase. 

“Currently, we are investing a great deal of money and time in avenues with high failure rates, while patients and their families wait,” said NIH Director Francis Collins. 

Source: http://www.iol.co.za/scitech/science/news/pharmaceutical-giants-to-join-us-initiative-1.1642418#.UvRJa_bBG2w

How Does RA Affect the Blood?

Posted by Jimbo | Posted in | Posted on 5:45 PM

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Anemia affects between one-half and two-thirds of all individuals with RA, is the condition that results when the number of red blood cells decreases notably. Anemia may develop as one of the consequences of longstanding inflammation, and its severity often reflects the activity of the arthritis.

Called the anemia of chronic disease, this type of anemia usually improves when the arthritis is brought under control. In some situations, the drug erythropoietin can be administered intravenously to increase red blood cell production temporarily. This medication can be used in a presurgical situation, when an individual wants to donate his own blood for a scheduled surgery.

The Stages of Rheumatoid Arthritis

Posted by Jimbo | Posted in | Posted on 5:43 PM

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Rheumatoid Arthritis can be put into five stages where each stage is characterized by the status of the uncontrolled inflammation that is present in the joints of the body.

Stage 1

This is when people with RA don’t have any symptoms of arthritis and their joints appear normal. Just because somebody has the RA gene marker, doesn’t mean that they will automatically develop it. The factors that actually trigger the development are still unknown. To make it even better, unknown factors trigger the inflammatory process and some other unknown trigger keeps going by not allowing the normal inflammation process to happen.

Rheumatic Fever Symptoms

Posted by Jimbo | Posted in | Posted on 5:41 PM

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People tend to have different rheumatic fever symptoms while some people only experience a few and the symptoms can change during the course of having it. Rheumatic fever is common all over the world (except in the United States) and has been responsible for damaging many heart valves. The last outbreak was recorded back in the 1980’s.

This disease will mainly affect children between the ages of 6-15 and is usually noticeable almost 20 days after there has been a case of scarlet fever or strep throat.

Osteoarthritis vs Rheumatoid Arthritis

Posted by Jimbo | Posted in | Posted on 5:36 PM

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When discussing Osteoarthritis vs Rheumatoid Arthritis, they are two very different types of diseases. Osteoarthritis primarily affects the cartilage that is between the joint. Rheumatoid arthritis (RA) is a disease that causes the soft tissues around the joint to become inflamed. Osteoarthritis will usually involve the fingers, knees, and hips. Rheumatoid arthritis will almost always involve the wrists and feet.

The reason we have joints in our body is to make the ability to move around as easy and comfortable as possible. If you imagine your elbow, it’s where both of your arm bones come together right? Both bones just don’t sit there inside your muscles, they are connected by a joint (kind of like a hinge) to allow movement and rotation. These joints are cushioned by a cushion called cartilage and there is a fluid in there called they synovial fluid. Depending on whether you have rheumatoid arthritis (RA) or osteoarthritis (OA) will determine how the joints are affected or damaged.

Seronegative Rheumatoid Arthritis

Posted by Jimbo | Posted in | Posted on 5:31 PM

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Is a type of rheumatoid arthritis where the blood doesn’t contain Rheumatoid Factor (RF or RhF).


By testing for Rheumatoid Factor in the blood, this is the most common way of diagnosing the presence of Seronegative Rheumatoid Arthritis. Testing for RF is not the only way but the most common. Even though you may test negative for it, several other tests are needed to verify. Let’s go over some of those:

erythrocyte sedimentation rate (ESR) – also called a sedimentation rate or Biernacki Reaction, is performed by placing blood that is not coagulated into an upright tube called a Westergren tube, and the rate that the red blood cells fall is measured and reported. X-rays

Rheumatoid Arthritis Diet

Posted by Jimbo | Posted in | Posted on 5:27 PM

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There are man books that claim they have the miracle rheumatoid arthritis diet on the shelves, but none of them really have any proven data to back them up. It sounds appealing but don’t just bet that you can control your RA just by changing your diet. I’m not saying that a proper diet isn’t helpful because it definitely is. What I am saying is that a diet alone won’t do the trick. I am promoting that following a healthy, balanced diet will play a key factor in your overall wellness.